Site Directed Spin Labeling

Molecular Biophysics is at the heart of understanding the complexities of biological systems at a molecular level. Fouad Sabry’s “Site Directed Spin Labeling” delves deep into the cuttingedge techniques used to probe protein structure and function, an essential part of biophysics that is integral for breakthroughs in scientific and medical fields. This book provides an indepth exploration of SiteDirected Spin Labeling (SDSL) and its applications in structural biology, offering essential insights for professionals, undergraduate and graduate students, and enthusiasts in the field

Sitedirected spin labeling-This chapter introduces SDSL, a powerful technique for studying molecular structures and dynamics of proteins using spin labels

Structural biology-It explores how SDSL aids in determining the 3D structures of proteins and their interaction with other molecules

Thylakoid-This chapter focuses on the structure of thylakoid membranes and their role in photosynthesis, analyzed using SDSL

Bacteriorhodopsin-The unique structural features of bacteriorhodopsin, a protein involved in light energy conversion, are examined with SDSL

Alphasynuclein-SDSL is applied to understand the structural and functional aspects of alphasynuclein, a protein linked to neurodegenerative diseases

Photosystem-This chapter discusses the photosystem, essential for photosynthesis, and how SDSL reveals its molecular structure and functioning

Photosystem I-An indepth look at Photosystem I, a key player in the light reactions of photosynthesis, analyzed using spin labeling techniques

Spin label-The fundamentals of spin labeling, including its chemical properties and applications in molecular biophysics, are explored here

Oxygenevolving complex-This chapter highlights the role of SDSL in studying the oxygenevolving complex, central to photosynthetic water splitting

Electron paramagnetic resonance-The application of electron paramagnetic resonance (EPR) spectroscopy in conjunction with SDSL for studying molecular dynamics is explained

Cytochrome b6f complex-The Cytochrome b6f complex, a crucial component of photosynthetic electron transport, is analyzed with SDSL techniques

Lightharvesting complexes of green plants-This chapter investigates how lightharvesting complexes function in plants, with spin labeling used to reveal their structure

Photosynthetic reaction centre-It provides an understanding of the photosynthetic reaction center, a key protein complex in energy conversion in photosynthesis

Wayne L. Hubbell-This chapter honors Wayne L. Hubbell’s contributions to SDSL and its application in studying molecular dynamics

Harden M. McConnell-Harden M. McConnell’s work on the application of SDSL in molecular biology and biochemistry is discussed

Photosynthetic reaction centre protein family-The evolution and molecular structure of the photosynthetic reaction center protein family are explored here

Albumin transport function analysis by EPR spectroscopy-The chapter describes how EPR spectroscopy and SDSL are applied to study albumin's transport function in cells

Wolfgang Lubitz-Wolfgang Lubitz’s groundbreaking work in biophysics, particularly on the oxygenevolving complex, is covered in this chapter

R. David Britt-This chapter focuses on R. David Britt’s research, contributing significantly to understanding electron transfer in photosynthesis

Daniella Goldfarb-The chapter highlights Daniella Goldfarb’s work in applying SDSL to investigate protein structures and interactions

Enrica Bordignon-Enrica Bordignon’s research in biophysics, particularly using EPR spectroscopy in SDSL, is featured in this final chapter