“Biomolecular Structure,” part of the Molecular Biophysics series, offers an indepth exploration of the structures that define life at the molecular level. This essential resource for professionals, undergraduate and graduate students, enthusiasts, and hobbyists bridges the fields of biochemistry, molecular biology, and bioinformatics, providing valuable insights into biomolecular interactions and structurefunction relationships. The book is a comprehensive guide to understanding the core principles and cuttingedge research shaping the future of molecular biophysics.
Chapters Brief Overview:
1: Biomolecular structure: Introduction to the fundamental structures of biomolecules, laying the foundation for the study of molecular biophysics.
2: Denaturation (biochemistry): Explores the process of protein denaturation, its biochemical implications, and its role in cellular functions.
3: Nucleic acid: Focuses on the structure and function of nucleic acids, the building blocks of genetic material and central players in molecular biophysics.
4: Protein biosynthesis: Examines the intricate process of protein synthesis and its critical role in cellular functioning.
5: Biomolecule: A detailed analysis of biomolecules, their diverse forms, and how they contribute to cellular processes and structure.
6: Structural bioinformatics: Introduces computational tools used to study biomolecular structures, enhancing our understanding of biological systems.
7: Hoogsteen base pair: Discusses the noncanonical base pairing in nucleic acids, highlighting its significance in DNA structure and function.
8: History of molecular biology: Traces the evolution of molecular biology and its impact on our understanding of biomolecular structures.
9: Nucleic acid structure prediction: Investigates methods for predicting nucleic acid structures, a key challenge in modern molecular biology.
10: Nucleic acid thermodynamics: Analyzes the thermodynamic principles governing nucleic acid stability and function.
11: Biomolecular engineering: Explores how biomolecular engineering shapes the development of new therapeutics and molecular tools.
12: Nucleic acid design: Focuses on designing synthetic nucleic acids for applications in biotechnology and medicine.
13: Nucleic acid structure determination: Examines techniques for determining the precise structures of nucleic acids.
14: Molecular models of DNA: Delivers insights into the structural modeling of DNA, providing a deeper understanding of its functions.
15: Nucleic acid tertiary structure: Focuses on the threedimensional structure of nucleic acids, essential for understanding their biological functions.
16: Nucleic acid structure: Provides a comprehensive study of nucleic acid structure, a cornerstone of molecular biology and biophysics.
17: Nucleic acid secondary structure: Explores the secondary structure of nucleic acids and its influence on their biological roles.
18: Triple helix: Investigates the concept of triplehelix structures in nucleic acids, expanding our understanding of genetic material.
19: Nucleic acid quaternary structure: Analyzes the quaternary structure of nucleic acids and its impact on cellular processes.
20: PSIPRED: Introduces PSIPRED, a powerful tool for predicting protein secondary structures, essential for structural bioinformatics.
21: Noncanonical base pairing: Discusses alternative base pairing in nucleic acids, offering a broader view of DNA/RNA structures.
This book is a critical resource for those seeking a deep understanding of molecular structures and their relevance to cellular functions. With each chapter building upon the last, “Biomolecular Structure” equips readers with a complete toolkit for navigating the complex and evolving field of molecular biophysics.